Pseudomonas aeruginosa PAO1, PA0154 (pcaG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0015976 carbon utilization
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0044248 cellular catabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0008199 ferric iron binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00775
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006725 cellular aromatic compound metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00775
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00775
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005506 iron ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:2.60.130.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:2.60.130.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0019439 aromatic compound catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02423
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0018578 protocatechuate 3,4-dioxygenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02423
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Carbon compound catabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01220 Degradation of aromatic compounds 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc 4-sulfocatechol degradation InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00362 Benzoate degradation 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Aromatic compound catabolism ECO:0000037
not_recorded
PseudoCyc PROTOCATECHUATE-ORTHO-CLEAVAGE-PWY protocatechuate degradation II (ortho-cleavage pathway) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd03463 3,4-PCD_alpha IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit 6 200 6.98058E-87
NCBIfam TIGR02423 JCVI: protocatechuate 3,4-dioxygenase subunit alpha IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit 9 201 8.8E-75
Gene3D G3DSA:2.60.130.10 Aromatic compound dioxygenase IPR015889 Intradiol ring-cleavage dioxygenase, core 3 201 1.2E-52
Pfam PF00775 Dioxygenase IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal 42 191 7.7E-12
SUPERFAMILY SSF49482 Aromatic compound dioxygenase IPR015889 Intradiol ring-cleavage dioxygenase, core 5 201 3.53E-57
FunFam G3DSA:2.60.130.10:FF:000001 Protocatechuate 3,4-dioxygenase alpha chain - - 2 201 1.8E-115
PANTHER PTHR33711 DIOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02910)-RELATED - - 4 200 3.6E-41

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.