Pseudomonas aeruginosa PAO1, PA0317

Annotation Updates

Date	Description	Acknowledgements
Dec 18, 2017	New PubMed ID: 28827360.	Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Oct 6, 2023	New comment: PA0317 is a D-2-hydroxyglutarate dehydrogenase that converts D-2-hydroxyglutarate to 2-ketoglutarate and its alternative substrate D-malate to oxaloacetate;Zinc and FAD-dependent enzyme whose electron acceptor is unknown and not oxygen. It uses 1 mole of zinc per mole of protein to orient and activate the substrate upon binding;The FAD serves as the reaction center for hydride transfer;PaD2HGDH is active with cobalt, manganese, nickel, or cadmium as an alternative metal. New PMIDs: 33301690, 36775126, 36775127.	Joanna Afokai Quaye, Department of Chemistry, Georgia State University, USA
Dec 18, 2017	New PseudoCAP Function Class: Amino acid biosynthesis and metabolism. New PubMed ID: 28827360.	Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada