Pseudomonas aeruginosa PAO1, PA0447 (gcdH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003995 acyl-CoA dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS00073
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00441
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0050660 flavin adenine dinucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:1.10.540.10
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00441
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class
Fatty acid and phospholipid metabolism Other PAO1 genes in this class
Carbon compound catabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCyc TRYPTOPHAN-DEGRADATION-1 L-tryptophan degradation III (eukaryotic) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
KEGG pae01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc PWY-5177 glutaryl-CoA degradation 19.5 ECO:0000250
sequence similarity evidence used in manual assertion
12867747
KEGG pae00071 Fatty acid degradation 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00310 Lysine degradation 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Fatty acid metabolism ECO:0000037
not_recorded
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Lysine degradation ECO:0000037
not_recorded
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Tryptophan metabolism ECO:0000037
not_recorded
KEGG pae00380 Tryptophan metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00362 Benzoate degradation 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal 20 132 1.2E-34
Pfam PF02770 Acyl-CoA dehydrogenase, middle domain IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain 136 227 6.2E-22
ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. IPR006089 Acyl-CoA dehydrogenase, conserved site 345 364 -
PIRSF PIRSF016578 149 391 3.1E-10
Gene3D G3DSA:1.10.540.10 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily 2 134 3.8E-42
SUPERFAMILY SSF47203 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal 243 390 3.54E-42
CDD cd01151 GCD 7 392 0.0
SUPERFAMILY SSF56645 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily 7 238 6.54E-77
Gene3D G3DSA:1.20.140.10 241 393 6.3E-42
Gene3D G3DSA:2.40.110.10 135 239 3.6E-38
PIRSF PIRSF016578 15 94 0.16
Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal 239 385 9.5E-28

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.