Pseudomonas aeruginosa PAO1, PA1337 (ansB)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0004067	asparaginase activity
Biological Process	GO:0006522	alanine metabolic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Biological Process	GO:0006520	cellular amino acid metabolic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Molecular Function	GO:0008854	exodeoxyribonuclease V activity	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Biological Process	GO:0006807	nitrogen compound metabolic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Molecular Function	GO:0004067	asparaginase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR00520	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006528	asparagine metabolic process	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR00520	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae02020	Two-component system	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae00471	D-Glutamine and D-glutamate metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae00220	Arginine biosynthesis	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae01110	Biosynthesis of secondary metabolites	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Alanine and Aspartate metabolism		ECO:0000037 not_recorded
PseudoCAP		Nitrogen metabolism		ECO:0000037 not_recorded
KEGG	pae01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae00250	Alanine, aspartate and glutamate metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Cyanoamino acid metabolism		ECO:0000037 not_recorded

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PRINTS	PR00139	Asparaginase/glutaminase family signature	IPR006034	Asparaginase/glutaminase-like	37	48	2.3E-21
NCBIfam	TIGR00520	JCVI: type II asparaginase	IPR004550	L-asparaginase, type II	25	362	1.5E-113
Gene3D	G3DSA:3.40.50.1170	-	IPR037152	L-asparaginase, N-terminal domain superfamily	35	247	3.4E-67
SUPERFAMILY	SSF53774	Glutaminase/Asparaginase	IPR036152	Asparaginase/glutaminase-like superfamily	34	361	5.1E-96
PANTHER	PTHR11707	L-ASPARAGINASE	IPR006034	Asparaginase/glutaminase-like	31	358	3.5E-40
Pfam	PF17763	Glutaminase/Asparaginase C-terminal domain	IPR040919	Asparaginase/glutaminase, C-terminal	249	359	6.1E-20
PIRSF	PIRSF001220	L-ASNase_gatD	IPR006034	Asparaginase/glutaminase-like	31	362	7.7E-86
CDD	cd00411	L-asparaginase_like	-	-	59	356	0.0
PIRSF	PIRSF500176	L_ASNase	-	-	33	362	1.4E-77
SMART	SM00870	Asparaginase_2	IPR006034	Asparaginase/glutaminase-like	36	356	5.7E-126
FunFam	G3DSA:3.40.50.1170:FF:000001	L-asparaginase 2	-	-	32	247	5.5E-76
Pfam	PF00710	Asparaginase, N-terminal	IPR027474	L-asparaginase, N-terminal	36	226	2.0E-54
Gene3D	G3DSA:3.40.50.40	-	IPR027473	L-asparaginase, C-terminal	249	361	3.9E-32
PRINTS	PR00139	Asparaginase/glutaminase family signature	IPR006034	Asparaginase/glutaminase-like	117	135	2.3E-21
PRINTS	PR00139	Asparaginase/glutaminase family signature	IPR006034	Asparaginase/glutaminase-like	295	313	2.3E-21

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.