Pseudomonas aeruginosa PAO1, PA1511 (vgrG2a)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1511
Name
vgrG2a
Replicon chromosome
Genomic location 1641497 - 1644025 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 10 transposon mutants in orthologs

Cross-References

RefSeq NP_250202.1
GI 15596708
Affymetrix PA1511_at
Entrez 883127
GenBank AAG04900.1
INSDC AAG04900.1
NCBI Locus Tag PA1511
protein_id(GenBank) gb|AAG04900.1|AE004579_12|gnl|PseudoCAP|PA1511
TIGR NTL03PA01512
UniParc UPI00000C53B8
UniProtKB Acc Q9I3K1
UniProtKB ID Q9I3K1_PSEAE
UniRef100 UniRef100_Q9I3K1
UniRef50 UniRef50_Q9I3K1
UniRef90 UniRef90_Q9I3K1

Product

Feature Type CDS
Coding Frame 1
Product Name
VgrG2a
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -12.07
Kyte-Doolittle Hydrophobicity Value -0.548
Molecular Weight (kDa) 93.6
Isoelectric Point (pI) 6.43

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 138 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000090 (3342 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1511
Search term: vgrG2a
Search term: VgrG2a

Human Homologs

References

Rhs elements comprise three subfamilies which diverged prior to acquisition by Escherichia coli.
Wang YD, Zhao S, Hill CW
J Bacteriol 1998 Aug;180(16):4102-10
PubMed ID: 9696756
Type VI secretion system in Pseudomonas aeruginosa: secretion and multimerization of VgrG proteins.
Hachani A, Lossi NS, Hamilton A, Jones C, Bleves S, Albesa-Jové D, Filloux A
J Biol Chem 2011 Apr 8;286(14):12317-27
PubMed ID: 21325275