Pseudomonas aeruginosa PAO1, PA1587 (lpd)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009405 pathogenesis
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 23071278 Reviewed by curator
Biological Process GO:0042783 evasion of host immune response
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 23071278 Reviewed by curator
Molecular Function GO:0004148 dihydrolipoyl dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01350
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF55424
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0050660 flavin adenine dinucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF55424
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Energy metabolism Other PAO1 genes in this class
Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00280 Valine, leucine and isoleucine degradation 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00020 Citrate cycle (TCA cycle) 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Pyruvate metabolism ECO:0000037
not_recorded
KEGG pae00260 Glycine, serine and threonine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00640 Propanoate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00620 Pyruvate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00630 Glyoxylate and dicarboxylate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00010 Glycolysis / Gluconeogenesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Glycolysis / Gluconeogenesis ECO:0000037
not_recorded
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Glycine, serine and threonine metabolism ECO:0000037
not_recorded
PseudoCAP Citrate cycle (TCA cycle) ECO:0000037
not_recorded
KEGG pae01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature - - 6 28 5.5E-82
Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 353 462 3.9E-39
SUPERFAMILY SSF51905 FAD/NAD(P)-binding domain IPR036188 FAD/NAD(P)-binding domain superfamily 1 344 5.1E-65
Gene3D G3DSA:3.50.50.60 - IPR036188 FAD/NAD(P)-binding domain superfamily 5 342 9.2E-130
PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature - - 414 429 5.5E-82
PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature - - 183 208 5.5E-82
NCBIfam TIGR01350 JCVI: dihydrolipoyl dehydrogenase IPR006258 Dihydrolipoamide dehydrogenase 4 472 0.0
PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature - - 271 285 5.5E-82
PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature - - 45 60 5.5E-82
PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature - - 436 456 5.5E-82
FunFam G3DSA:3.50.50.60:FF:000272 Dihydrolipoyl dehydrogenase - - 163 284 3.2E-77
PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature - - 147 156 5.5E-82
FunFam G3DSA:3.30.390.30:FF:000001 Dihydrolipoyl dehydrogenase - - 352 472 2.1E-50
Gene3D G3DSA:3.50.50.60 - IPR036188 FAD/NAD(P)-binding domain superfamily 163 284 9.2E-130
PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature - - 7 26 8.5E-42
PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature - - 299 321 8.5E-42
PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature - - 270 286 8.5E-42
PANTHER PTHR22912 DISULFIDE OXIDOREDUCTASE - - 3 466 0.0
PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature - - 314 321 5.5E-82
PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature - - 183 201 8.5E-42
Gene3D G3DSA:3.30.390.30 - IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily 352 478 6.0E-51
PIRSF PIRSF000350 Hg-II_reductase_MerA IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I 1 471 2.9E-90
SUPERFAMILY SSF55424 FAD/NAD-linked reductases, dimerisation (C-terminal) domain IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily 349 473 2.58E-42
PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature - - 144 162 8.5E-42
PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature - - 349 370 5.5E-82
Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase IPR023753 FAD/NAD(P)-binding domain 5 334 2.5E-70

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.