Pseudomonas aeruginosa PAO1, PA2385 (pvdQ)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Cellular Component	GO:0005737	cytoplasm	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	22498339	Reviewed by curator
Biological Process	GO:0002049	pyoverdine biosynthetic process	IMP Inferred from Mutant Phenotype	ECO:0000315 mutant phenotype evidence used in manual assertion	21892836	Reviewed by curator
Biological Process	GO:0071978	bacterial-type flagellum-dependent swarming motility	IEP Inferred from Expression Pattern	ECO:0000270 expression evidence used in manual assertion	18245294	Reviewed by curator
Biological Process	GO:0002049	pyoverdine biosynthetic process	IMP Inferred from Mutant Phenotype	ECO:0000315 mutant phenotype evidence used in manual assertion	19787431	Reviewed by curator
Biological Process	GO:0071978	bacterial-type flagellum-dependent swarming motility	IMP Inferred from Mutant Phenotype	ECO:0000315 mutant phenotype evidence used in manual assertion	18245294	Reviewed by curator
Biological Process	GO:0002049	pyoverdine biosynthetic process	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	22498339	Reviewed by curator
Molecular Function	GO:0047379	ADP-dependent short-chain-acyl-CoA hydrolase activity	IMP Inferred from Mutant Phenotype	ECO:0000315 mutant phenotype evidence used in manual assertion	21892836	Reviewed by curator
Molecular Function	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	IDA Inferred from Direct Assay	ECO:0000314 direct assay evidence used in manual assertion	16495538	Reviewed by curator
Biological Process	GO:0009405	pathogenesis	IMP Inferred from Mutant Phenotype	ECO:0000315 mutant phenotype evidence used in manual assertion	19778968	Reviewed by curator
Biological Process	GO:0044010	single-species biofilm formation	IMP Inferred from Mutant Phenotype	ECO:0000315 mutant phenotype evidence used in manual assertion	19778968	Reviewed by curator
Molecular Function	GO:0009392	N-acetyl-anhydromuramoyl-L-alanine amidase activity
Biological Process	GO:0002049	pyoverdine biosynthetic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	12686626	Reviewed by curator
Biological Process	GO:0002049	pyoverdine biosynthetic process	IMP Inferred from Mutant Phenotype	ECO:0000315 mutant phenotype evidence used in manual assertion	12686626	Reviewed by curator
Biological Process	GO:0050896	response to stimulus	IDA Inferred from Direct Assay	ECO:0000002 direct assay evidence
Biological Process	GO:0071978	bacterial-type flagellum-dependent swarming motility	IGI Inferred from Genetic Interaction	ECO:0000316 genetic interaction evidence used in manual assertion	19778968	Reviewed by curator
Biological Process	GO:0046677	response to antibiotic	IMP Inferred from Mutant Phenotype	ECO:0000315 mutant phenotype evidence used in manual assertion	21833667	Reviewed by curator
Biological Process	GO:0017000	antibiotic biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:PTHR34218	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	ISM Inferred from Sequence Model Term mapped from: InterPro:PIRSF001227	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0016787	hydrolase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PTHR34218	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Adaptation, Protection Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
PseudoCAP		Pyoverdine synthesis		ECO:0000037 not_recorded
PseudoCyc	PYRNUCYC-PWY	pyridine nucleotide cycling	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
PseudoCyc	P345-PWY	aldoxime degradation	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
PIRSF	PIRSF001227	Pen_acylase	IPR014395	Penicillin/GL-7-ACA/AHL acylase	10	153	5.5E-14
CDD	cd01936	Ntn_CA	-	-	35	744	0.0
Gene3D	G3DSA:3.60.20.10	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1	IPR029055	Nucleophile aminohydrolases, N-terminal	217	748	0.0
Gene3D	G3DSA:1.10.439.10	Penicillin Amidohydrolase, domain 1	IPR023343	Penicillin amidase type, domain 1	25	192	4.8E-61
PANTHER	PTHR34218	PEPTIDASE S45 PENICILLIN AMIDASE	IPR002692	Penicillin/GL-7-ACA/AHL/aculeacin-A acylase	5	760	0.0
FunFam	G3DSA:1.10.439.10:FF:000003	Acyl-homoserine lactone acylase PvdQ	-	-	24	193	9.2E-118
SUPERFAMILY	SSF56235	N-terminal nucleophile aminohydrolases (Ntn hydrolases)	IPR029055	Nucleophile aminohydrolases, N-terminal	33	756	0.0
Gene3D	G3DSA:2.30.120.10	-	IPR043146	Penicillin amidase type, N-terminal domain, B-knob	292	366	0.0
PIRSF	PIRSF001227	Pen_acylase	IPR014395	Penicillin/GL-7-ACA/AHL acylase	179	759	2.0E-55
Pfam	PF01804	Penicillin amidase	IPR002692	Penicillin/GL-7-ACA/AHL/aculeacin-A acylase	33	750	0.0
Gene3D	G3DSA:1.10.1400.10	-	IPR043147	Penicillin amidase type, A-knob	509	690	0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.