Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA2407
|
Name |
fpvC
|
Replicon | chromosome |
Genomic location | 2690160 - 2691113 (+ strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Comment | Part ABC transporter complex FpvWXYZCDEF coded by operons fpvWXYZCDEF and fpvF. |
Comment | Structural similarity to 1XVL (Mn transporter from Synechocystis 6803, root-mean-square deviation: 0.9 angstroms). Sequence similarity to 1PSZ (97%/23,84%) (ZN). Final predicted ligand: metal Ion (PMID: 31631799) |
RefSeq | NP_251097.1 |
GI | 15597603 |
Affymetrix | PA2407_at |
DNASU | PaCD00007047 |
Entrez | 879560 |
GenBank | AAG05795.1 |
INSDC | AAG05795.1 |
NCBI Locus Tag | PA2407 |
protein_id(GenBank) | gb|AAG05795.1|AE004668_5|gnl|PseudoCAP|PA2407 |
TIGR | NTL03PA02407 |
UniParc | UPI00000C56B6 |
UniProtKB Acc | Q9I174 |
UniProtKB ID | Q9I174_PSEAE |
UniRef100 | UniRef100_A0A069PX18 |
UniRef50 | UniRef50_Q884F2 |
UniRef90 | UniRef90_A6V577 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
FpvC
|
Synonyms |
probable adhesion protein |
Evidence for Translation |
Detected by MALDI-TOF/TOF (PMID:19333994).
|
Charge (pH 7) | 6.68 |
Kyte-Doolittle Hydrophobicity Value | -0.032 |
Molecular Weight (kDa) | 34.3 |
Isoelectric Point (pI) | 9.60 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
6RU4 | TRANSPORT PROTEIN | 05/27/19 | Structure of the SBP FpvC from pseudomonas aeruginosa in complex with Mn2+ | Pseudomonas aeruginosa PAO1 | 2.49 | X-RAY DIFFRACTION | 100.0 |
6R44 | TRANSPORT PROTEIN | 03/21/19 | Structure of the SBP FpvC in complex with Ni2+ ion from P.aeruginosa from P21 space group | Pseudomonas aeruginosa PAO1 | 1.99 | X-RAY DIFFRACTION | 100.0 |
6R6K | PROTEIN TRANSPORT | 03/27/19 | Structure of a FpvC mutant from pseudomonas aeruginosa | Pseudomonas aeruginosa | 2.1 | X-RAY DIFFRACTION | 97.9 |
6R5S | TRANSPORT PROTEIN | 03/25/19 | Structure of the SBP FpvC from pseudomonas aeruginosa in complex with Fe(II) | Pseudomonas aeruginosa | 2.75 | X-RAY DIFFRACTION | 100.0 |
6R3Z | TRANSPORT PROTEIN | 03/21/19 | Structure of the SBP FpvC in complex with Ni2+ ion from P. aeruginosa in P212121 space group | Pseudomonas aeruginosa PAO1 | 1.65 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 473 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG003125 (477 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA2407
Search term: fpvC
Search term: FpvC
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|
Iron Release from the Siderophore Pyoverdine in Pseudomonas aeruginosa Involves Three New Actors: FpvC, FpvG, and FpvH.
Ganne G, Brillet K, Basta B, Roche B, Hoegy F, Gasser V, Schalk IJ
ACS Chem Biol 2017 Apr 21;12(4):1056-1065
PubMed ID: 28192658
|
An ABC transporter with two periplasmic binding proteins involved in iron acquisition in Pseudomonas aeruginosa.
Brillet K, Ruffenach F, Adams H, Journet L, Gasser V, Hoegy F, Guillon L, Hannauer M, Page A, Schalk IJ
ACS Chem Biol 2012 Dec 21;7(12):2036-45
PubMed ID: 23009327
|
The Two-Operon-Coded ABC Transporter Complex FpvWXYZCDEF is Required for Pseudomonas aeruginosa Growth and Virulence Under Iron-Limiting Conditions.
Gao L, Guo Z, Wang Y, Wang Y, Wang K, Li B, Shen L
J Membr Biol 2018 Feb;251(1):91-104
PubMed ID: 28975384
|
Uncovering the structure and function of Pseudomonas aeruginosa periplasmic proteins by an in silico approach.
Caprari S, Brandi V, Pasquadibisceglie A, Polticelli F
J Biomol Struct Dyn 2020 Sep;38(15):4508-4520
PubMed ID: 31631799
|