Pseudomonas aeruginosa PAO1, PA3190

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3190
Name
Replicon chromosome
Genomic location 3580384 - 3581646 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_251880.1
GI 15598386
Affymetrix PA3190_at
Entrez 882901
GenBank AAG06578.1
INSDC AAG06578.1
NCBI Locus Tag PA3190
protein_id(GenBank) gb|AAG06578.1|AE004743_1|gnl|PseudoCAP|PA3190
TIGR NTL03PA03190
UniParc UPI00000C5941
UniProtKB Acc Q9HZ48
UniProtKB ID Q9HZ48_PSEAE
UniRef100 UniRef100_W0YUY0
UniRef50 UniRef50_H0PSQ1
UniRef90 UniRef90_A6V2N5

Product

Feature Type CDS
Coding Frame 1
Product Name
probable binding protein component of ABC sugar transporter
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Detected by iTRAQ (PMID:21863142).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.91
Kyte-Doolittle Hydrophobicity Value -0.143
Molecular Weight (kDa) 45.1
Isoelectric Point (pI) 5.77

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 165 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002426 (525 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3190

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Characterization, occurrence, and molecular cloning of a 39-kilodalton Brucella abortus cytoplasmic protein immunodominant in cattle.
Denoel PA, Vo TK, Tibor A, Weynants VE, Trunde JM, Dubray G, Limet JN, Letesson JJ
Infect Immun 1997 Feb;65(2):495-502
PubMed ID: 9009303
Comparisons of Two Proteomic Analyses of Non-Mucoid and Mucoid Pseudomonas aeruginosa Clinical Isolates from a Cystic Fibrosis Patient.
Rao J, Damron FH, Basler M, Digiandomenico A, Sherman NE, Fox JW, Mekalanos JJ, Goldberg JB
Front Microbiol 2011;2:162
PubMed ID: 21863142