Pseudomonas aeruginosa PAO1, PA3649 (mucP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0005886 plasma membrane
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 21036998 Reviewed by curator
Molecular Function GO:0008237 metallopeptidase activity
ISO
Inferred from Sequence Orthology
Term mapped from: UniProtKB:P0AEH1
 ECO:0000266
sequence orthology evidence used in manual assertion		 9234758 Reviewed by curator
Biological Process GO:0007165 signal transduction
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 21036998 Reviewed by curator
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00054
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006508 proteolysis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00054
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005515 protein binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF13180
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004222 metalloendopeptidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00054
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Hypothetical, unclassified, unknown Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae02024 Quorum sensing 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd00989 PDZ_metalloprotease - - 211 287 6.88345E-24
CDD cd06163 S2P-M50_PDZ_RseP-like - - 7 121 2.80255E-49
Gene3D G3DSA:2.30.42.10 - IPR036034 PDZ superfamily 125 220 1.8E-25
PANTHER PTHR42837 REGULATOR OF SIGMA-E PROTEASE RSEP IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase 216 450 8.9E-113
NCBIfam TIGR00054 JCVI: RIP metalloprotease RseP IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase 2 450 2.3E-123
SUPERFAMILY SSF50156 PDZ domain-like IPR036034 PDZ superfamily 87 181 9.2E-15
Pfam PF02163 Peptidase family M50 IPR008915 Peptidase M50 224 436 2.7E-60
SUPERFAMILY SSF50156 PDZ domain-like IPR036034 PDZ superfamily 208 290 1.97E-16
CDD cd06163 S2P-M50_PDZ_RseP-like - - 379 449 2.80101E-31
Pfam PF02163 Peptidase family M50 IPR008915 Peptidase M50 10 193 6.1E-59
SMART SM00228 pdz_new IPR001478 PDZ domain 114 186 8.4E-6
Pfam PF17820 PDZ domain IPR041489 PDZ domain 6 129 161 3.6E-7
Pfam PF13180 PDZ domain IPR001478 PDZ domain 225 289 1.6E-10
Gene3D G3DSA:2.30.42.10 - IPR036034 PDZ superfamily 221 306 1.8E-18
CDD cd00989 PDZ_metalloprotease - - 111 195 3.87742E-14
SMART SM00228 pdz_new IPR001478 PDZ domain 211 280 3.2E-8

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.