Pseudomonas aeruginosa PAO1, PA4418 (ftsI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0043093 FtsZ-dependent cytokinesis
IDA
Inferred from Direct Assay
ECO:0000002
direct assay evidence
Molecular Function GO:0008658 penicillin binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03717
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0051301 cell division
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02080
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009252 peptidoglycan biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02080
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008955 peptidoglycan glycosyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02080
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005886 plasma membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02080
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Cell division Other PAO1 genes in this class
Cell wall / LPS / capsule Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae00550 Peptidoglycan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01501 beta-Lactam resistance 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Peptideglycan biosynthesis ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Hamap MF_02080 Peptidoglycan D,D-transpeptidase FtsI [ftsI]. IPR037532 Peptidoglycan D,D-transpeptidase FtsI 4 575 42.454285
Pfam PF03717 Penicillin-binding Protein dimerisation domain IPR005311 Penicillin-binding protein, dimerisation domain 58 207 2.2E-17
PANTHER PTHR30627 PEPTIDOGLYCAN D,D-TRANSPEPTIDASE - - 11 559 0.0
Gene3D G3DSA:3.90.1310.10 - - - 50 221 1.8E-49
MobiDBLite mobidb-lite consensus disorder prediction - - 558 579 -
SUPERFAMILY SSF56601 beta-lactamase/transpeptidase-like IPR012338 Beta-lactamase/transpeptidase-like 174 561 8.54E-92
FunFam G3DSA:3.90.1310.10:FF:000003 Peptidoglycan D,D-transpeptidase FtsI - - 50 221 4.8E-78
Pfam PF00905 Penicillin binding protein transpeptidase domain IPR001460 Penicillin-binding protein, transpeptidase 247 546 4.4E-86
SUPERFAMILY SSF56519 Penicillin binding protein dimerisation domain IPR036138 Penicillin-binding protein, dimerisation domain superfamily 54 221 1.83E-44
Gene3D G3DSA:3.30.450.330 - - - 223 550 7.8E-125
Gene3D G3DSA:3.40.710.10 - IPR012338 Beta-lactamase/transpeptidase-like 283 464 7.8E-125

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.