Pseudomonas aeruginosa PAO1, PA4759 (dapB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004425 indole-3-glycerol-phosphate synthase activity
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Biological Process GO:0006520 cellular amino acid metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0009085 lysine biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0009089 lysine biosynthetic process via diaminopimelate
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000161
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008839 4-hydroxy-tetrahydrodipicolinate reductase
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000161
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00261 Monobactam biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00300 Lysine biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Lysine biosynthesis ECO:0000037
not_recorded
KEGG pae01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF01113 Dihydrodipicolinate reductase, N-terminus IPR000846 Dihydrodipicolinate reductase, N-terminal 3 126 1.5E-39
Gene3D G3DSA:3.30.360.10 Dihydrodipicolinate Reductase; domain 2 - - 128 235 1.3E-118
Gene3D G3DSA:3.40.50.720 - - - 3 265 1.3E-118
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 1 267 3.23E-50
Pfam PF05173 Dihydrodipicolinate reductase, C-terminus IPR022663 Dihydrodipicolinate reductase, C-terminal 129 265 6.8E-44
PANTHER PTHR20836 DIHYDRODIPICOLINATE REDUCTASE IPR023940 Dihydrodipicolinate reductase 4 265 2.6E-50
FunFam G3DSA:3.30.360.10:FF:000004 4-hydroxy-tetrahydrodipicolinate reductase - - 128 235 1.3E-54
FunFam G3DSA:3.40.50.720:FF:000048 4-hydroxy-tetrahydrodipicolinate reductase - - 2 131 3.9E-46
NCBIfam TIGR00036 JCVI: 4-hydroxy-tetrahydrodipicolinate reductase IPR023940 Dihydrodipicolinate reductase 3 266 4.9E-100
Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. IPR023940 Dihydrodipicolinate reductase 2 265 36.423985
PIRSF PIRSF000161 DHPR IPR023940 Dihydrodipicolinate reductase 1 268 3.9E-88
SUPERFAMILY SSF55347 Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain - - 128 237 1.79E-37

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.