Pseudomonas aeruginosa PAO1, PA5086 (tli5b1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5086
Name
tli5b1
Replicon chromosome
Genomic location 5724601 - 5725242 (- strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_253773
GI 15600279
Affymetrix PA5086_at
GenBank AAG08471.1
protein_id(GenBank) gb|AAG08471.1|AE004921_8|gnl|PseudoCAP|PA5086
TIGR NTL03PA05087
UniProtKB Acc Q9HU97
UniProtKB ID Q9HU97_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
type VI secretion lipase immunity protein, Tli5b1
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) -1.09
Kyte-Doolittle Hydrophobicity Value -0.470
Molecular Weight (kDa) 23.8
Isoelectric Point (pI) 6.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6LCH PROTEIN BINDING 11/19/19 Pseudomonas aeruginosa 5086 (PA5086) Pseudomonas aeruginosa 1.899 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 52 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005159 (5 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5086
Search term: tli5b1

Human Homologs

References

The T6SSs of Pseudomonas aeruginosa Strain PAO1 and Their Effectors: Beyond Bacterial-Cell Targeting.
Sana TG, Berni B, Bleves S
Front Cell Infect Microbiol 2016;6:61
PubMed ID: 27376031