Pseudomonas aeruginosa PAO1, PA0010 (tag)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0010
Name
tag
Replicon chromosome
Genomic location 13540 - 14091 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_248700.1
GI 15595208
Affymetrix PA0010_tag_at
DNASU PaCD00006007
Entrez 878076
GenBank AAG03400.1
INSDC AAG03400.1
NCBI Locus Tag PA0010
protein_id(GenBank) gb|AAG03400.1|AE004441_1|gnl|PseudoCAP|PA0010
TIGR NTL03PA00011
UniParc UPI00000C4EE5
UniProtKB Acc Q9I7B6
UniProtKB ID Q9I7B6_PSEAE
UniRef100 UniRef100_W0YLR1
UniRef50 UniRef50_A0A090ITZ8
UniRef90 UniRef90_A6UX71

Product

Feature Type CDS
Coding Frame 1
Product Name
DNA-3-methyladenine glycosidase I
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -7.40
Kyte-Doolittle Hydrophobicity Value -0.225
Molecular Weight (kDa) 20.8
Isoelectric Point (pI) 4.63

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 355 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000010 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0010
Search term: tag

Human Homologs

References

Nucleotide sequence of the tag gene from Escherichia coli.
Steinum AL, Seeberg E
Nucleic Acids Res 1986 May 12;14(9):3763-72
PubMed ID: 3520491
Purification and structure of 3-methyladenine-DNA glycosylase I of Escherichia coli.
Sakumi K, Nakabeppu Y, Yamamoto Y, Kawabata S, Iwanaga S, Sekiguchi M
J Biol Chem 1986 Nov 25;261(33):15761-6
PubMed ID: 3536912
Different efficiencies of the Tag and AlkA DNA glycosylases from Escherichia coli in the removal of 3-methyladenine from single-stranded DNA.
Bjelland S, Seeberg E
FEBS Lett 1996 Nov 11;397(1):127-9
PubMed ID: 8941728