Strain |
Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest |
Locus Tag |
PA14_19010
|
Name |
tsi3
|
Replicon | chromosome |
Genomic location | 1641698 - 1642135 (- strand) |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | YP_789662.1 |
GI | 116051503 |
Entrez | 4381469 |
INSDC | ABJ12739.1 |
NCBI Locus Tag | PA14_19010 |
UniParc | UPI00003960CB |
UniProtKB Acc | Q02QX4 |
UniProtKB ID | Q02QX4_PSEAB |
UniRef100 | UniRef100_Q02QX4 |
UniRef50 | UniRef50_A6V1U0 |
UniRef90 | UniRef90_Q02QX4 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
Tsi3
|
Synonyms |
hypothetical protein |
Evidence for Translation | |
Charge (pH 7) | -3.79 |
Kyte-Doolittle Hydrophobicity Value | -0.450 |
Molecular Weight (kDa) | 15.8 |
Isoelectric Point (pI) | 4.85 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
8IK3 | IMMUNE SYSTEM | 02/28/23 | Structure of Stimulator of interferon genes/ligand complex | Homo sapiens | 3.3 | ELECTRON MICROSCOPY | 99.2 |
8IK0 | IMMUNE SYSTEM | 02/28/23 | Cryo-EM structure of Stimulator of interferon genes | Gallus gallus; Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) | 3.3 | ELECTRON MICROSCOPY | 99.2 |
4LUQ | PROTEIN BINDING/TOXIN INHIBITOR | 07/25/13 | Crystal structure of virulence effector Tse3 in complex with neutralizer Tsi3 | Pseudomonas aeruginosa | 1.77 | X-RAY DIFFRACTION | 97.6 |
4M5F | HYDROLASE INHIBITOR | 08/08/13 | complex structure of Tse3-Tsi3 | Pseudomonas aeruginosa | 2.5 | X-RAY DIFFRACTION | 99.2 |
3WA5 | HYDROLASE | 04/26/13 | Crystal Structure of type VI peptidoglycan muramidase effector Tse3 in complex with its cognate immunity protein Tsi3 | Pseudomonas aeruginosa | 1.9 | X-RAY DIFFRACTION | 98.6 |
4N80 | HYDROLASE/HYDROLASE INHIBITOR | 10/16/13 | Crystal structure of Tse3-Tsi3 complex | Pseudomonas aeruginosa | 2.4 | X-RAY DIFFRACTION | 97.6 |
4N7S | HYDROLASE/HYDROLASE INHIBITOR | 10/16/13 | Crystal structure of Tse3-Tsi3 complex with Zinc ion | Pseudomonas aeruginosa | 2.101 | X-RAY DIFFRACTION | 99.2 |
4N88 | HYDROLASE/HYDROLASE INHIBITOR | 10/17/13 | Crystal structure of Tse3-Tsi3 complex with calcium ion | Pseudomonas aeruginosa | 2.8 | X-RAY DIFFRACTION | 99.2 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 2 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG002157 (299 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA14_19010
Search term: tsi3
Search term: Tsi3
|
RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.
Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A
Proc Natl Acad Sci U S A 2017 Jul 18;114(29):7707-7712
PubMed ID: 28673999
|
Structural insights into the T6SS effector protein Tse3 and the Tse3-Tsi3 complex from Pseudomonas aeruginosa reveal a calcium-dependent membrane-binding mechanism.
Lu D, Shang G, Zhang H, Yu Q, Cong X, Yuan J, He F, Zhu C, Zhao Y, Yin K, Chen Y, Hu J, Zhang X, Yuan Z, Xu S, Hu W, Cang H, Gu L
Mol Microbiol 2014 Jun;92(5):1092-112
PubMed ID: 24724564
|