Pseudomonas aeruginosa PA7, PSPA7_4641 (exlB)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PA7
GCF_000017205.1|latest |
| Locus Tag |
PSPA7_4641
|
| Name |
exlB
|
| Replicon | chromosome |
| Genomic location | 4764521 - 4766233 (+ strand) |
| Comment | 100% identical to ExlB in Pseudomonas aeruginosa PA7 (PSPA7_4641) |
Cross-References
| RefSeq | YP_001349985.1 |
| GI | 152987369 |
| Entrez | 5357947 |
| NCBI Locus Tag | PSPA7_4641 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
ExlB
|
| Synonyms |
hemolysin activator protein |
| Evidence for Translation | |
| Charge (pH 7) | 10.60 |
| Kyte-Doolittle Hydrophobicity Value | -0.373 |
| Molecular Weight (kDa) | 62.9 |
| Isoelectric Point (pI) | 9.61 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 111 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG020747 (52 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PSPA7_4641
Search term: exlB
Search term: ExlB
|
Human Homologs
References
|
A type III secretion negative clinical strain of Pseudomonas aeruginosa employs a two-partner secreted exolysin to induce hemorrhagic pneumonia.
Elsen S, Huber P, Bouillot S, Couté Y, Fournier P, Dubois Y, Timsit JF, Maurin M, Attrée I
Cell Host Microbe 2014 Feb 12;15(2):164-76
PubMed ID: 24528863
|