Pseudomonas aeruginosa PAO1, PA0253 (hudR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0253
Name
hudR
Replicon chromosome
Genomic location 284197 - 284673 (- strand)
Transposon Mutants 1 transposon mutants in PAO1

Cross-References

RefSeq NP_248944.1
GI 15595450
Affymetrix PA0253_at
DNASU PaCD00006114
Entrez 881936
GenBank AAG03642.1
NCBI Locus Tag PA0253
protein_id(GenBank) gb|AAG03642.1|AE004463_7|gnl|PseudoCAP|PA0253
TIGR NTL03PA00254
UniProtKB Acc Q9I6N6
UniProtKB ID Q9I6N6_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
HudR
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -0.28
Kyte-Doolittle Hydrophobicity Value -0.075
Molecular Weight (kDa) 17.4
Isoelectric Point (pI) 6.81

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 61 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000251 (296 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0253
Search term: hudR
Search term: HudR

Human Homologs

References

The Salmonella typhimurium mar locus: molecular and genetic analyses and assessment of its role in virulence.
Sulavik MC, Dazer M, Miller PF
J Bacteriol 1997 Mar;179(6):1857-66
PubMed ID: 9068629
Drosophila melanogaster-based screening for multihost virulence factors of Pseudomonas aeruginosa PA14 and identification of a virulence-attenuating factor, HudA.
Kim SH, Park SY, Heo YJ, Cho YH
Infect Immun 2008 Sep;76(9):4152-62
PubMed ID: 18591226