Pseudomonas aeruginosa PAO1, PA0361

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0361
Name
Replicon chromosome
Genomic location 404386 - 406119 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_249052.1
GI 15595558
Affymetrix PA0361_at
Entrez 879505
GenBank AAG03750.1
INSDC AAG03750.1
NCBI Locus Tag PA0361
protein_id(GenBank) gb|AAG03750.1|AE004474_2|gnl|PseudoCAP|PA0361
TIGR NTL03PA00362
UniParc UPI00000C5027
UniProtKB Acc Q9I6D3
UniProtKB ID Q9I6D3_PSEAE
UniRef100 UniRef100_S0JCE7
UniRef50 UniRef50_V5BXC1
UniRef90 UniRef90_A6UYG5

Product

Feature Type CDS
Coding Frame 1
Product Name
probable gamma-glutamyltranspeptidase precursor
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 6.15
Kyte-Doolittle Hydrophobicity Value -0.236
Molecular Weight (kDa) 62.1
Isoelectric Point (pI) 9.15

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Periplasmic Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 393 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000352 (854 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0361

Human Homologs

Ensembl 110, assembly GRCh38.p14
gamma-glutamyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4250]
E-value: 6.2e-46
Percent Identity: 29.4
Ensembl 110, assembly GRCh38.p14
gamma-glutamyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:4250]
E-value: 6.2e-46
Percent Identity: 29.4

References

gamma-Glutamyltranspeptidase from Escherichia coli K-12: purification and properties.
Suzuki H, Kumagai H, Tochikura T
J Bacteriol 1986 Dec;168(3):1325-31
PubMed ID: 2877974
Bacterial gamma-glutamyltranspeptidases: comparison of Escherichia coli and Pseudomonas gamma-glutamyltranspeptidase.
Ishiye M, Niwa M
FEMS Microbiol Lett 1992 Oct 15;76(3):235-41
PubMed ID: 1358750
Molecular cloning of the gamma-glutamyltranspeptidase gene from a Pseudomonas strain.
Ishiye M, Yamashita M, Niwa M
Biotechnol Prog 1993 May-Jun;9(3):323-31
PubMed ID: 7765305
Subunit association of gamma-glutamyltranspeptidase of Escherichia coli K-12.
Hashimoto W, Suzuki H, Nohara S, Tachi H, Yamamoto K, Kumagai H
J Biochem 1995 Dec;118(6):1216-23
PubMed ID: 8720138
A preliminary description of the crystal structure of gamma-glutamyltranspeptidase from E. coli K-12.
Sakai H, Sakabe N, Sasaki K, Hashimoto W, Suzuki H, Tachi H, Kumagai H, Sakabe K
J Biochem 1996 Jul;120(1):26-8
PubMed ID: 8864839