Pseudomonas aeruginosa PAO1, PA0382 (micA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0382
Name
micA
Synonym: yggH
Replicon chromosome
Genomic location 424670 - 425341 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249073.1
GI 15595579
Affymetrix PA0382_micA_at
DNASU PaCD00006164
Entrez 879787
GenBank AAG03771.1
INSDC AAG03771.1
NCBI Locus Tag PA0382
protein_id(GenBank) gb|AAG03771.1|AE004476_1|gnl|PseudoCAP|PA0382
TIGR NTL03PA00383
UniParc UPI000012F6B0
UniProtKB Acc Q9I6B3
UniProtKB ID TRMB_PSEAE
UniRef100 UniRef100_Q9I6B3
UniRef50 UniRef50_Q48CM0
UniRef90 UniRef90_Q9I6B3

Product

Feature Type CDS
Coding Frame 1
Product Name
DNA mismatch repair protein MicA
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 3.10
Kyte-Doolittle Hydrophobicity Value -0.385
Molecular Weight (kDa) 25.3
Isoelectric Point (pI) 8.28

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 478 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000373 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0382
Search term: micA

Human Homologs

References

Nucleotide sequence of the Escherichia coli micA gene required for A/G-specific mismatch repair: identity of micA and mutY.
Tsai-Wu JJ, Radicella JP, Lu AL
J Bacteriol 1991 Mar;173(6):1902-10
PubMed ID: 2001994