Pseudomonas aeruginosa PAO1, PA0463 (creB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0463
Name
creB
Replicon chromosome
Genomic location 523254 - 523943 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249154.1
GI 15595660
Affymetrix PA0463_creB_at
DNASU PaCD00006192
Entrez 881852
GenBank AAG03852.1
INSDC AAG03852.1
NCBI Locus Tag PA0463
protein_id(GenBank) gb|AAG03852.1|AE004484_4|gnl|PseudoCAP|PA0463
TIGR NTL03PA00464
UniParc UPI00000C506D
UniProtKB Acc Q9I655
UniProtKB ID Q9I655_PSEAE
UniRef100 UniRef100_W0YLM0
UniRef50 UniRef50_Q4K4R2
UniRef90 UniRef90_Q02TV0

Product

Feature Type CDS
Coding Frame 1
Product Name
two-component response regulator CreB
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -5.58
Kyte-Doolittle Hydrophobicity Value -0.192
Molecular Weight (kDa) 25.6
Isoelectric Point (pI) 5.40

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 619 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000455 (466 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0463
Search term: creB

Human Homologs

References

Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes.
Burland V, Plunkett G 3rd, Sofia HJ, Daniels DL, Blattner FR
Nucleic Acids Res 1995 Jun 25;23(12):2105-19
PubMed ID: 7610040