Pseudomonas aeruginosa PAO1, PA0471 (fiuR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0471
Name
fiuR
Synonym: fiuR
Replicon chromosome
Genomic location 532541 - 533512 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249162.1
GI 15595668
Affymetrix PA0471_at
DNASU PaCD00006196
Entrez 879576
GenBank AAG03860.1
INSDC AAG03860.1
NCBI Locus Tag PA0471
protein_id(GenBank) gb|AAG03860.1|AE004485_1|gnl|PseudoCAP|PA0471
TIGR NTL03PA00472
UniParc UPI00000C5075
UniProtKB Acc Q9I647
UniProtKB ID Q9I647_PSEAE
UniRef100 UniRef100_W0YLU7
UniRef50 UniRef50_A0A077JKA4
UniRef90 UniRef90_A0A077JKA4

Product

Feature Type CDS
Coding Frame 1
Product Name
FiuR
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 3.41
Kyte-Doolittle Hydrophobicity Value -0.177
Molecular Weight (kDa) 35.4
Isoelectric Point (pI) 8.92

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 136 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000462 (1708 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0471
Search term: fiuR
Search term: FiuR

Human Homologs

References

Gene repression by the ferric uptake regulator in Pseudomonas aeruginosa: cycle selection of iron-regulated genes.
Ochsner UA, Vasil ML
Proc Natl Acad Sci U S A 1996 Apr 30;93(9):4409-14
PubMed ID: 8633080
The heterologous siderophores ferrioxamine B and ferrichrome activate signaling pathways in Pseudomonas aeruginosa.
Llamas MA, Sparrius M, Kloet R, Jiménez CR, Vandenbroucke-Grauls C, Bitter W
J Bacteriol 2006 Mar;188(5):1882-91
PubMed ID: 16484199