Pseudomonas aeruginosa PAO1, PA0727

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0727
Name
Replicon chromosome
Genomic location 794501 - 795793 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249418.1
GI 15595924
Affymetrix PA0727_at
Entrez 880742
GenBank AAG04116.1
INSDC AAG04116.1
NCBI Locus Tag PA0727
protein_id(GenBank) gb|AAG04116.1|AE004508_1|gnl|PseudoCAP|PA0727
TIGR NTL03PA00728
UniParc UPI00000C5123
UniProtKB Acc Q9I5K1
UniProtKB ID Q9I5K1_PSEAE
UniRef100 UniRef100_Q9I5K1
UniRef50 UniRef50_P25130
UniRef90 UniRef90_P25130

Product

Feature Type CDS
Coding Frame 1
Product Name
Pf replication initiator protein
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 5.10
Kyte-Doolittle Hydrophobicity Value -0.380
Molecular Weight (kDa) 49.3
Isoelectric Point (pI) 7.98

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 4 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000703 (278 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0727

Human Homologs

References

Excisionase in Pf filamentous prophage controls lysis-lysogeny decision-making in Pseudomonas aeruginosa.
Li Y, Liu X, Tang K, Wang P, Zeng Z, Guo Y, Wang X
Mol Microbiol 2019 Feb;111(2):495-513
PubMed ID: 30475408
Pf Filamentous Phage Requires UvrD for Replication in Pseudomonas aeruginosa.
Martínez E, Campos-Gómez J
mSphere 2016 Jan-Feb;1(1)
PubMed ID: 27303696