Pseudomonas aeruginosa PAO1, PA0746

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0746
Name
Replicon chromosome
Genomic location 813329 - 814492 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249437.1
GI 15595943
Affymetrix PA0746_at
Entrez 879393
GenBank AAG04135.1
INSDC AAG04135.1
NCBI Locus Tag PA0746
protein_id(GenBank) gb|AAG04135.1|AE004509_10|gnl|PseudoCAP|PA0746
TIGR NTL03PA00747
UniParc UPI00000C5135
UniProtKB Acc Q9I5I3
UniProtKB ID Q9I5I3_PSEAE
UniRef100 UniRef100_A0A072ZLS2
UniRef50 UniRef50_Q9UKU7
UniRef90 UniRef90_S6AHM4

Product

Feature Type CDS
Coding Frame 1
Product Name
probable acyl-CoA dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -7.54
Kyte-Doolittle Hydrophobicity Value -0.171
Molecular Weight (kDa) 42.6
Isoelectric Point (pI) 5.33

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 477 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000720 (316 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0746

Human Homologs

Ensembl 110, assembly GRCh38.p14
acyl-CoA dehydrogenase family member 8 [Source:HGNC Symbol;Acc:HGNC:87]
E-value: 3.7e-119
Percent Identity: 54.9

References

No references are associated with this feature.