Pseudomonas aeruginosa PAO1, PA0848 (ahpB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0848
Name
ahpB
Replicon chromosome
Genomic location 927147 - 927746 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249539.1
GI 15596045
Affymetrix PA0848_at
DNASU PaCD00006389
Entrez 877588
GenBank AAG04237.1
INSDC AAG04237.1
NCBI Locus Tag PA0848
protein_id(GenBank) gb|AAG04237.1|AE004519_8|gnl|PseudoCAP|PA0848
TIGR NTL03PA00849
UniParc UPI00000C5187
UniProtKB Acc Q9I593
UniProtKB ID Q9I593_PSEAE
UniRef100 UniRef100_W0YMI8
UniRef50 UniRef50_B9KDK9
UniRef90 UniRef90_A6VAD1

Product

Feature Type CDS
Coding Frame 1
Product Name
alkyl hydroperoxide reductase , AhpB
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -7.38
Kyte-Doolittle Hydrophobicity Value 0.029
Molecular Weight (kDa) 21.8
Isoelectric Point (pI) 5.08

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 617 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000815 (310 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0848
Search term: ahpB

Human Homologs

Ensembl 110, assembly GRCh38.p14
peroxiredoxin 2 [Source:HGNC Symbol;Acc:HGNC:9353]
E-value: 2.4e-53
Percent Identity: 51.0

References

Iron-responsive gene regulation in a campylobacter jejuni fur mutant.
van Vliet AH, Wooldridge KG, Ketley JM
J Bacteriol 1998 Oct;180(20):5291-8
PubMed ID: 9765558