Pseudomonas aeruginosa PAO1, PA0866 (aroP2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0866
Name
aroP2
Replicon chromosome
Genomic location 947205 - 948623 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq NP_249557.1
GI 15596063
Affymetrix PA0866_aroP2_at
Entrez 882250
GenBank AAG04255.1
INSDC AAG04255.1
NCBI Locus Tag PA0866
protein_id(GenBank) gb|AAG04255.1|AE004521_6|gnl|PseudoCAP|PA0866
TIGR NTL03PA00867
UniParc UPI00000C5198
UniProtKB Acc Q9I575
UniProtKB ID Q9I575_PSEAE
UniRef100 UniRef100_Q9I575
UniRef50 UniRef50_P15993
UniRef90 UniRef90_Q9I575

Product

Feature Type CDS
Coding Frame 1
Product Name
aromatic amino acid transport protein AroP2
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 12.47
Kyte-Doolittle Hydrophobicity Value 0.704
Molecular Weight (kDa) 51.3
Isoelectric Point (pI) 9.56

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 349 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000833 (831 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0866
Search term: aroP2

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Cloning of the aroP gene and identification of its product in Escherichia coli K-12.
Chye ML, Guest JR, Pittard J
J Bacteriol 1986 Aug;167(2):749-53
PubMed ID: 3015892
Nucleotide sequence of the aroP gene encoding the general aromatic amino acid transport protein of Escherichia coli K-12: homology with yeast transport proteins.
Honoré N, Cole ST
Nucleic Acids Res 1990 Feb 11;18(3):653
PubMed ID: 2408019