Pseudomonas aeruginosa PAO1, PA1019 (mucK)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1019
Name
mucK
Replicon chromosome
Genomic location 1104009 - 1105364 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249710.1
GI 15596216
Affymetrix PA1019_mucK_at
Entrez 879387
GenBank AAG04408.1
INSDC AAG04408.1
NCBI Locus Tag PA1019
protein_id(GenBank) gb|AAG04408.1|AE004534_6|gnl|PseudoCAP|PA1019
TIGR NTL03PA01020
UniParc UPI00000C5207
UniProtKB Acc Q9I4V5
UniProtKB ID Q9I4V5_PSEAE
UniRef100 UniRef100_Q9I4V5
UniRef50 UniRef50_P94131
UniRef90 UniRef90_Q9I4V5

Product

Feature Type CDS
Coding Frame 1
Product Name
cis,cis-muconate transporter MucK
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 8.46
Kyte-Doolittle Hydrophobicity Value 0.557
Molecular Weight (kDa) 48.0
Isoelectric Point (pI) 8.99

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 379 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000981 (315 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1019
Search term: mucK

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
mucK, a gene in Acinetobacter calcoaceticus ADP1 (BD413), encodes the ability to grow on exogenous cis,cis-muconate as the sole carbon source.
Williams PA, Shaw LE
J Bacteriol 1997 Sep;179(18):5935-42
PubMed ID: 9294455