Pseudomonas aeruginosa PAO1, PA1072 (braE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1072
Name
braE
Replicon chromosome
Genomic location 1159422 - 1160675 (- strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249763.1
GI 15596269
Affymetrix PA1072_braE_at
Entrez 880501
GenBank AAG04461.1
INSDC AAG04461.1
NCBI Locus Tag PA1072
protein_id(GenBank) gb|AAG04461.1|AE004539_3|gnl|PseudoCAP|PA1072
TIGR NTL03PA01073
UniParc UPI0000126AB9
UniProtKB Acc P21628
UniProtKB ID BRAE_PSEAE
UniRef100 UniRef100_P21628
UniRef50 UniRef50_P22729
UniRef90 UniRef90_P21628

Product

Feature Type CDS
Coding Frame 1
Product Name
branched-chain amino acid transport protein BraE
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 12.44
Kyte-Doolittle Hydrophobicity Value 0.854
Molecular Weight (kDa) 45.6
Isoelectric Point (pI) 10.26

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 1
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 423 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001034 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1072
Search term: braE

Human Homologs

References

Cloning, nucleotide sequences, and identification of products of the Pseudomonas aeruginosa PAO bra genes, which encode the high-affinity branched-chain amino acid transport system.
Hoshino T, Kose K
J Bacteriol 1990 Oct;172(10):5531-9
PubMed ID: 2120183