Pseudomonas aeruginosa PAO1, PA1161 (rrmA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1161
Name
rrmA
Replicon chromosome
Genomic location 1258488 - 1259291 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249852.1
GI 15596358
Affymetrix PA1161_rrmA_at
Entrez 877757
GenBank AAG04550.1
INSDC AAG04550.1
NCBI Locus Tag PA1161
protein_id(GenBank) gb|AAG04550.1|AE004546_5|gnl|PseudoCAP|PA1161
TIGR NTL03PA01162
UniParc UPI00000C527F
UniProtKB Acc Q9I4H6
UniProtKB ID Q9I4H6_PSEAE
UniRef100 UniRef100_Q9I4H6
UniRef50 UniRef50_F6ACI9
UniRef90 UniRef90_Q9I4H6

Product

Feature Type CDS
Coding Frame 1
Product Name
rRNA methyltransferase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 2.50
Kyte-Doolittle Hydrophobicity Value -0.221
Molecular Weight (kDa) 29.6
Isoelectric Point (pI) 7.85

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 140 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001120 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1161
Search term: rrmA

Human Homologs

References

Identification of the rrmA gene encoding the 23S rRNA m1G745 methyltransferase in Escherichia coli and characterization of an m1G745-deficient mutant.
Gustafsson C, Persson BC
J Bacteriol 1998 Jan;180(2):359-65
PubMed ID: 9440525