Pseudomonas aeruginosa PAO1, PA1162 (dapE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1162
Name
dapE
Replicon chromosome
Genomic location 1259291 - 1260442 (- strand)
Transposon Mutants 1 transposon mutants in PAO1

Cross-References

RefSeq NP_249853.1
GI 15596359
Affymetrix PA1162_dapE_at
DNASU PaCD00006534
Entrez 877783
GenBank AAG04551.1
INSDC AAG04551.1
NCBI Locus Tag PA1162
protein_id(GenBank) gb|AAG04551.1|AE004546_6|gnl|PseudoCAP|PA1162
TIGR NTL03PA01163
UniParc UPI00000C5280
UniProtKB Acc Q9I4H5
UniProtKB ID DAPE_PSEAE
UniRef100 UniRef100_B7UX27
UniRef50 UniRef50_Q9KQ52
UniRef90 UniRef90_A6V936

Product

Feature Type CDS
Coding Frame 1
Product Name
succinyl-diaminopimelate desuccinylase
Product Name Confidence: Class 2
Synonyms N-succinyl-diaminopimelate deacylase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -14.01
Kyte-Doolittle Hydrophobicity Value -0.033
Molecular Weight (kDa) 41.1
Isoelectric Point (pI) 5.01

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 489 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001121 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1162
Search term: dapE

Human Homologs

References

Cloning, characterization, and expression of the dapE gene of Escherichia coli.
Bouvier J, Richaud C, Higgins W, Bögler O, Stragier P
J Bacteriol 1992 Aug;174(16):5265-71
PubMed ID: 1644752