Pseudomonas aeruginosa PAO1, PA1202

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1202
Name
Synonym: ycaC
Replicon chromosome
Genomic location 1302696 - 1303313 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249893.1
GI 15596399
Affymetrix PA1202_at
DNASU PaCD00006556
Entrez 882011
GenBank AAG04591.1
INSDC AAG04591.1
NCBI Locus Tag PA1202
protein_id(GenBank) gb|AAG04591.1|AE004550_7|gnl|PseudoCAP|PA1202
TIGR NTL03PA01203
UniParc UPI00000C52A5
UniProtKB Acc Q9I4D6
UniProtKB ID Q9I4D6_PSEAE
UniRef100 UniRef100_W0YMC9
UniRef50 UniRef50_C7ZM58
UniRef90 UniRef90_W0YMC9

Product

Feature Type CDS
Coding Frame 1
Product Name
probable hydrolase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -5.35
Kyte-Doolittle Hydrophobicity Value 0.056
Molecular Weight (kDa) 22.5
Isoelectric Point (pI) 4.83

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4WGF HYDROLASE 09/18/14 YcaC from Pseudomonas aeruginosa with hexane-2,5-diol and covalent acrylamide Pseudomonas aeruginosa 2.34021 X-RAY DIFFRACTION 100.0
4WH0 HYDROLASE 09/19/14 YcaC from Pseudomonas aeruginosa with S-mercaptocysteine active site cysteine Pseudomonas aeruginosa 2.563 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 193 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001159 (872 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1202

Human Homologs

References

The 1.8 A crystal structure of the ycaC gene product from Escherichia coli reveals an octameric hydrolase of unknown specificity.
Colovos C, Cascio D, Yeates TO
Structure 1998 Oct 15;6(10):1329-37
PubMed ID: 9782055