Pseudomonas aeruginosa PAO1, PA1236

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA1236
Name
Replicon chromosome
Genomic location 1336430 - 1337941 (- strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_249927.1
GI 15596433
Affymetrix PA1236_at
Entrez 881177
GenBank AAG04625.1
INSDC AAG04625.1
NCBI Locus Tag PA1236
protein_id(GenBank) gb|AAG04625.1|AE004553_2|gnl|PseudoCAP|PA1236
TIGR NTL03PA01237
UniParc UPI00000C52C5
UniProtKB Acc Q9I4A2
UniProtKB ID Q9I4A2_PSEAE
UniRef100 UniRef100_W0YLC1
UniRef50 UniRef50_D4E494
UniRef90 UniRef90_W0YLC1

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Evidence for Translation
Charge (pH 7) 6.81
Kyte-Doolittle Hydrophobicity Value 0.686
Molecular Weight (kDa) 54.0
Isoelectric Point (pI) 9.20

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff E-value Percent Identity CARD Version
farB farB is the cytoplasmic transporter protein that is part of the farAB efflux pump. ARO:3003962 protein homolog model Strict 0.0 0.28481 1.1.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 480 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001188 (358 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1236

Transposon Insertions in PAO1

Type ISlacZ/hah insertion site
Mutant ID UWGC: 19973
Genomic Position 1336477
Position in ORF 48(1512)
Reference 14617778
Type Confirmed ISlacZ/hah insertion site
Mutant ID UWGC: 13543
Genomic Position 1336740
Position in ORF 311(1512)
Reference 14617778

Transposon Insertions in Orthologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res. 2005 Feb;15(2):321-9
PubMed ID: 15687295
Emr, an Escherichia coli locus for multidrug resistance.
Lomovskaya O, Lewis K
Proc. Natl. Acad. Sci. U.S.A. 1992 Oct;89(19):8938-42
PubMed ID: 1409590