Pseudomonas aeruginosa PAO1, PA1316

Cytoplasmic Membrane
Outer Membrane
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
Replicon chromosome
Genomic location 1425912 - 1427453 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 7 transposon mutants in orthologs


RefSeq NP_250007.1
GI 15596513
Affymetrix PA1316_at
Entrez 881564
GenBank AAG04705.1
INSDC AAG04705.1
NCBI Locus Tag PA1316
protein_id(GenBank) gb|AAG04705.1|AE004561_1|gnl|PseudoCAP|PA1316
UniParc UPI00000C530B
UniProtKB Acc Q9I428
UniRef100 UniRef100_A0A0C6EL89
UniRef50 UniRef50_G2E188
UniRef90 UniRef90_A6V8P4


Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Charge (pH 7) 6.55
Kyte-Doolittle Hydrophobicity Value 0.843
Molecular Weight (kDa) 53.1
Isoelectric Point (pI) 9.16

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff E-value Percent Identity CARD Version
lrfA lfrA is involved in the active efflux of quinolones and is found in Mycobacterium smegmatis. ARO:3003967 protein homolog model Strict 1.11487E-38 0.320896 1.1.8

Pathogen Association Analysis

Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 541 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001213 (1431 members)
Putative Inparalogs None Found


STRING database Search for predicted protein-protein interactions using:
Search term: PA1316


Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res. 2005 Feb;15(2):321-9
PubMed ID: 15687295
Nucleotide sequence analysis reveals similarities between proteins determining methylenomycin A resistance in Streptomyces and tetracycline resistance in eubacteria.
Neal RJ, Chater KF
Gene 1987 ;58(2-3):229-41
PubMed ID: 2828187
Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin.
Bibb MJ, Sherman DH, Omura S, Hopwood DA
Gene 1994 May;142(1):31-9
PubMed ID: 8181754
Cloning and sequence analysis of the putative rifamycin polyketide synthase gene cluster from Amycolatopsis mediterranei.
Schupp T, Toupet C, Engel N, Goff S
FEMS Microbiol. Lett. 1998 Feb;159(2):201-7
PubMed ID: 9503613