Pseudomonas aeruginosa PAO1, PA1396

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1396
Name
Replicon chromosome
Genomic location 1517146 - 1518768 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250087.1
GI 15596593
Affymetrix PA1396_at
Entrez 879363
GenBank AAG04785.1
INSDC AAG04785.1
NCBI Locus Tag PA1396
protein_id(GenBank) gb|AAG04785.1|AE004569_3|gnl|PseudoCAP|PA1396
TIGR NTL03PA01397
UniParc UPI00000C5359
UniProtKB Acc Q9I3U8
UniProtKB ID Q9I3U8_PSEAE
UniRef100 UniRef100_Q9I3U8
UniRef50 UniRef50_Q4K6Y4
UniRef90 UniRef90_Q9I3U8

Product

Feature Type CDS
Coding Frame 1
Product Name
probable two-component sensor
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 9.42
Kyte-Doolittle Hydrophobicity Value 0.028
Molecular Weight (kDa) 60.4
Isoelectric Point (pI) 8.84

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 616 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001317 (407 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1396

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Molecular characterization of the phenylacetic acid catabolic pathway in Pseudomonas putida U: the phenylacetyl-CoA catabolon.
Olivera ER, Miñambres B, García B, Muñiz C, Moreno MA, Ferrández A, Díaz E, García JL, Luengo JM
Proc Natl Acad Sci U S A 1998 May 26;95(11):6419-24
PubMed ID: 9600981