Pseudomonas aeruginosa PAO1, PA1436

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA1436
Name
Replicon chromosome
Genomic location 1563967 - 1567077 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_250127.1
GI 15596633
Affymetrix PA1436_at
Entrez 881815
GenBank AAG04825.1
INSDC AAG04825.1
NCBI Locus Tag PA1436
protein_id(GenBank) gb|AAG04825.1|AE004573_4|gnl|PseudoCAP|PA1436
TIGR NTL03PA01437
UniParc UPI00000C537E
UniProtKB Acc Q9I3R1
UniProtKB ID Q9I3R1_PSEAE
UniRef100 UniRef100_S0I9G1
UniRef50 UniRef50_A0A085UAG0
UniRef90 UniRef90_B7UWB6

Product

Feature Type CDS
Coding Frame 1
Product Name
probable Resistance-Nodulation-Cell Division (RND) efflux transporter
Product Name Confidence: Class 3
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -7.38
Kyte-Doolittle Hydrophobicity Value 0.445
Molecular Weight (kDa) 110.8
Isoelectric Point (pI) 5.88

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff E-value Percent Identity CARD Version
mdtC MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB, MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. ARO:3000794 protein homolog model Strict 0.0 0.999035 1.1.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 487 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001353 (1589 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1436

Transposon Insertions in PAO1

Type Confirmed ISlacZ/hah insertion site
Mutant ID UWGC: 9314
Genomic Position 1564588
Position in ORF 622(3111)
Reference 14617778
Type Confirmed ISlacZ/hah insertion site
Mutant ID UWGC: 7760
Genomic Position 1565925
Position in ORF 1959(3111)
Reference 14617778

Transposon Insertions in Orthologs

References

No references are associated with this feature.