Pseudomonas aeruginosa PAO1, PA1444 (fliN)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1444
Name
fliN
Replicon chromosome
Genomic location 1573551 - 1574024 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250135.1
GI 15596641
Affymetrix PA1444_fliN_at
DNASU PaCD00006664
Entrez 881851
GenBank AAG04833.1
INSDC AAG04833.1
NCBI Locus Tag PA1444
protein_id(GenBank) gb|AAG04833.1|AE004574_4|gnl|PseudoCAP|PA1444
TIGR NTL03PA01445
UniParc UPI000012A9D8
UniProtKB Acc Q51466
UniProtKB ID FLIN_PSEAE
UniRef100 UniRef100_Q51466
UniRef50 UniRef50_Q51466
UniRef90 UniRef90_Q51466

Product

Feature Type CDS
Coding Frame 1
Product Name
flagellar motor switch protein FliN
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -16.51
Kyte-Doolittle Hydrophobicity Value -0.039
Molecular Weight (kDa) 16.6
Isoelectric Point (pI) 3.97

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0273
Category Flagella
Evidence
Host Organism
Notes
Reference 14617143

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 313 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001361 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1444
Search term: fliN

Human Homologs

References

FliN is a major structural protein of the C-ring in the Salmonella typhimurium flagellar basal body.
Zhao R, Pathak N, Jaffe H, Reese TS, Khan S
J Mol Biol 1996 Aug 16;261(2):195-208
PubMed ID: 8757287