Pseudomonas aeruginosa UCBPP-PA14, PA14_01600

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_01600
Name
Replicon chromosome
Genomic location 145477 - 146970 (- strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq YP_788288.1
GI 116053851
Entrez 4384247
INSDC ABJ15087.1
NCBI Locus Tag PA14_01600
UniParc UPI00000C4F52
UniProtKB Acc Q02UU8
UniProtKB ID Q02UU8_PSEAB
UniRef100 UniRef100_Q9I702
UniRef50 UniRef50_Q9I702
UniRef90 UniRef90_Q9I702

Product

Feature Type CDS
Coding Frame 1
Product Name
aldehyde dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -7.37
Kyte-Doolittle Hydrophobicity Value -0.014
Molecular Weight (kDa) 53.3
Isoelectric Point (pI) 5.95

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5TJR OXIDOREDUCTASE 10/05/16 X-ray Crystal structure of a methylmalonate semialdehyde dehydrogenase from Pseudomonas sp. AAC Pseudomonas sp. AAC 2.95 X-RAY DIFFRACTION 91.5

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 599 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000128 (531 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_01600

Human Homologs

Ensembl 110, assembly GRCh38.p14
aldehyde dehydrogenase 6 family member A1 [Source:HGNC Symbol;Acc:HGNC:7179]
E-value: 2.3e-126
Percent Identity: 45.6

References

No references are associated with this feature.