Pseudomonas aeruginosa PAO1, PA1972

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA1972
Name
Replicon chromosome
Genomic location 2153594 - 2155297 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_250662.1
GI 15597168
Affymetrix PA1972_at
Entrez 881487
GenBank AAG05360.1
INSDC AAG05360.1
NCBI Locus Tag PA1972
protein_id(GenBank) gb|AAG05360.1|AE004623_10|gnl|PseudoCAP|PA1972
TIGR NTL03PA01972
UniParc UPI00000C5539
UniProtKB Acc Q9I2D3
UniProtKB ID Q9I2D3_PSEAE
UniRef100 UniRef100_Q9I2D3
UniRef50 UniRef50_S2FPC3
UniRef90 UniRef90_Q9I2D3

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Evidence for Translation
Charge (pH 7) 0.08
Kyte-Doolittle Hydrophobicity Value 0.040
Molecular Weight (kDa) 62.3
Isoelectric Point (pI) 7.01

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff E-value Percent Identity CARD Version
PmrC PmrC mediates the modification of Lipid A by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) and phosphoethanolamine, resulting in a less negative cell membrane and decreased binding of polymyxin B. ARO:3003576 protein homolog model Strict 0.0 0.426923 1.1.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 137 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003461 (914 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1972

Transposon Insertions in PAO1

Type Confirmed ISlacZ/hah insertion site
Mutant ID UWGC: 21946
Genomic Position 2155196
Position in ORF 1603(1704)
Reference 14617778
Type Confirmed ISlacZ/hah insertion site
Mutant ID UWGC: 16509
Genomic Position 2154790
Position in ORF 1197(1704)
Reference 14617778

Transposon Insertions in Orthologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res. 2005 Feb;15(2):321-9
PubMed ID: 15687295