Pseudomonas aeruginosa PAO1, PA2389 (pvdR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA2389
Name
pvdR
Replicon chromosome
Genomic location 2642131 - 2643306 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_251079.1
GI 15597585
Affymetrix PA2389_at
DNASU PaCD00007043
Entrez 882270
GenBank AAG05777.1
INSDC AAG05777.1
NCBI Locus Tag PA2389
protein_id(GenBank) gb|AAG05777.1|AE004665_4|gnl|PseudoCAP|PA2389
TIGR NTL03PA02389
UniParc UPI00000C56A8
UniProtKB Acc Q9I191
UniProtKB ID Q9I191_PSEAE
UniRef100 UniRef100_Q9I191
UniRef50 UniRef50_Q9I191
UniRef90 UniRef90_Q9I191

Product

Feature Type CDS
Coding Frame 1
Product Name
PvdR
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) 4.69
Kyte-Doolittle Hydrophobicity Value -0.302
Molecular Weight (kDa) 42.1
Isoelectric Point (pI) 9.45

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff E-value Percent Identity CARD Version
macA MacA is a membrane fusion protein that forms an antibiotic efflux complex with MacB and TolC. ARO:3000533 protein homolog model Strict 0.0 0.365439 1.1.8

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 468 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003138 (499 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2389
Search term: pvdR
Search term: PvdR

Transposon Insertions in PAO1

Type ISphoA/hah insertion site
Mutant ID UWGC: 32408
Genomic Position 2642410
Position in ORF 280(1176)
Reference 14617778
Type ISphoA/hah insertion site
Mutant ID UWGC: 42636
Genomic Position 2642432
Position in ORF 302(1176)
Reference 14617778

Transposon Insertions in Orthologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res. 2005 Feb;15(2):321-9
PubMed ID: 15687295
Molecular basis of pyoverdine siderophore recycling in Pseudomonas aeruginosa.
Imperi F, Tiburzi F, Visca P
Proc. Natl. Acad. Sci. U.S.A. 2009 Dec;106(48):20440-5
PubMed ID: 19906986