Pseudomonas aeruginosa PAO1, PA0155 (pcaR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0155
Name
pcaR
Replicon chromosome
Genomic location 176315 - 177154 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_248845.1
GI 15595353
Affymetrix PA0155_pcaR_at
DNASU PaCD00006067
Entrez 882136
GenBank AAG03545.1
INSDC AAG03545.1
NCBI Locus Tag PA0155
protein_id(GenBank) gb|AAG03545.1|AE004453_8|gnl|PseudoCAP|PA0155
TIGR NTL03PA00156
UniParc UPI00000C4F6A
UniProtKB Acc Q9I6X7
UniProtKB ID Q9I6X7_PSEAE
UniRef100 UniRef100_W0YK42
UniRef50 UniRef50_Q52154
UniRef90 UniRef90_A6UXU4

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator PcaR
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 2.25
Kyte-Doolittle Hydrophobicity Value 0.051
Molecular Weight (kDa) 30.6
Isoelectric Point (pI) 7.62

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 330 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000153 (612 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0155
Search term: pcaR

Human Homologs

References

Characterization of the pcaR regulatory gene from Pseudomonas putida, which is required for the complete degradation of p-hydroxybenzoate.
Romero-Steiner S, Parales RE, Harwood CS, Houghton JE
J Bacteriol 1994 Sep;176(18):5771-9
PubMed ID: 8083169