Pseudomonas aeruginosa PAO1, PA0438 (codB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0438
Name
codB
Replicon chromosome
Genomic location 490648 - 491898 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_249129.1
GI 15595635
Affymetrix PA0438_codB_at
Entrez 877581
GenBank AAG03827.1
INSDC AAG03827.1
NCBI Locus Tag PA0438
protein_id(GenBank) gb|AAG03827.1|AE004481_3|gnl|PseudoCAP|PA0438
TIGR NTL03PA00439
UniParc UPI00000C5055
UniProtKB Acc Q9I679
UniProtKB ID Q9I679_PSEAE
UniRef100 UniRef100_W0YJZ3
UniRef50 UniRef50_Q8X691
UniRef90 UniRef90_A6UYP9

Product

Feature Type CDS
Coding Frame 1
Product Name
cytosine permease
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 5.33
Kyte-Doolittle Hydrophobicity Value 0.890
Molecular Weight (kDa) 43.0
Isoelectric Point (pI) 9.06

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 2
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 142 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000429 (406 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0438
Search term: codB
Search term: cytosine permease

Human Homologs

References

Characterization of the Escherichia coli codBA operon encoding cytosine permease and cytosine deaminase.
Danielsen S, Kilstrup M, Barilla K, Jochimsen B, Neuhard J
Mol Microbiol 1992 May;6(10):1335-44
PubMed ID: 1640834