Pseudomonas aeruginosa PAO1, PA0446

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0446
Name
Replicon chromosome
Genomic location 501376 - 502599 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249137.1
GI 15595643
Affymetrix PA0446_at
Entrez 880393
GenBank AAG03835.1
INSDC AAG03835.1
NCBI Locus Tag PA0446
protein_id(GenBank) gb|AAG03835.1|AE004482_2|gnl|PseudoCAP|PA0446
TIGR NTL03PA00447
UniParc UPI00000C505C
UniProtKB Acc Q9I672
UniProtKB ID Q9I672_PSEAE
UniRef100 UniRef100_W0YLK3
UniRef50 UniRef50_Q0K3D9
UniRef90 UniRef90_B7V431

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -8.16
Kyte-Doolittle Hydrophobicity Value -0.125
Molecular Weight (kDa) 43.8
Isoelectric Point (pI) 5.27

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 312 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000437 (532 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0446

Human Homologs

Ensembl 110, assembly GRCh38.p14
succinyl-CoA:glutarate-CoA transferase [Source:HGNC Symbol;Acc:HGNC:16001]
E-value: 3.8e-98
Percent Identity: 44.9

References

No references are associated with this feature.