Pseudomonas aeruginosa PAO1, PA1124 (dgt)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA1124
Name
dgt
Replicon chromosome
Genomic location 1216671 - 1218167 (+ strand)
Transposon Mutants 5 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_249815.1
GI 15596321
Affymetrix PA1124_dgt_at
Entrez 880761
GenBank AAG04513.1
INSDC AAG04513.1
NCBI Locus Tag PA1124
protein_id(GenBank) gb|AAG04513.1|AE004542_9|gnl|PseudoCAP|PA1124
TIGR NTL03PA01125
UniParc UPI000012923F
UniProtKB Acc Q9I4L1
UniProtKB ID DGTP_PSEAE
UniRef100 UniRef100_Q9I4L1
UniRef50 UniRef50_Q9I4L1
UniRef90 UniRef90_Q9I4L1

Product

Feature Type CDS
Coding Frame 1
Product Name
deoxyguanosinetriphosphate triphosphohydrolase
Product Name Confidence: Class 2
Synonyms dGTPase
dGTP triphosphohydrolase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -4.77
Kyte-Doolittle Hydrophobicity Value -0.353
Molecular Weight (kDa) 56.7
Isoelectric Point (pI) 6.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 444 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001084 (331 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1124
Search term: dgt

References

The purification and properties of deoxyguanosine triphosphate triphosphohydrolase from Escherichia coli.
Seto D, Bhatnagar SK, Bessman MJ
J. Biol. Chem. 1988 Jan;263(3):1494-9
PubMed ID: 2826481