Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA1510
|
Name |
tplE
Synonym: tle4 |
Replicon | chromosome |
Genomic location | 1639791 - 1641500 (- strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
RefSeq | NP_250201.1 |
GI | 15596707 |
Affymetrix | PA1510_at |
Entrez | 879265 |
GenBank | AAG04899.1 |
INSDC | AAG04899.1 |
NCBI Locus Tag | PA1510 |
protein_id(GenBank) | gb|AAG04899.1|AE004579_11|gnl|PseudoCAP|PA1510 |
TIGR | NTL03PA01511 |
UniParc | UPI00000C53B7 |
UniProtKB Acc | Q9I3K2 |
UniProtKB ID | Q9I3K2_PSEAE |
UniRef100 | UniRef100_Q9I3K2 |
UniRef50 | UniRef50_Q9I3K2 |
UniRef90 | UniRef90_Q9I3K2 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
type 6 PGAP1-like effector, TplE
|
Synonyms |
Tle4 |
Evidence for Translation | |
Charge (pH 7) | -14.21 |
Kyte-Doolittle Hydrophobicity Value | -0.636 |
Molecular Weight (kDa) | 63.3 |
Isoelectric Point (pI) | 5.13 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
4R1D | HYDROLASE/HYDROLASE INHIBITOR | 08/05/14 | The crystal structure of Tle4-Tli4 complex | Pseudomonas aeruginosa PAO1 | 1.749 | X-RAY DIFFRACTION | 100.0 |
5H7Y | HYDROLASE INHIBITOR/PEPTIDE | 11/21/16 | Structure of immunity protein TplEi of T6SS from Pseudomonas aeruginosa complexed with L peptide | Pseudomonas aeruginosa PAO1 | 2.195 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 18 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG003845 (309 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA1510
Search term: tplE
Search term: type 6 PGAP1-like effector, TplE
|
Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors.
Russell AB, LeRoux M, Hathazi K, Agnello DM, Ishikawa T, Wiggins PA, Wai SN, Mougous JD
Nature 2013 Apr 25;496(7446):508-12
PubMed ID: 23552891
|
The Pseudomonas aeruginosa Type VI Secretion PGAP1-like Effector Induces Host Autophagy by Activating Endoplasmic Reticulum Stress.
Jiang F, Wang X, Wang B, Chen L, Zhao Z, Waterfield NR, Yang G, Jin Q
Cell Rep 2016 Aug 9;16(6):1502-1509
PubMed ID: 27477276
|