Pseudomonas aeruginosa PAO1, PA2322 (gntP)

Cytoplasmic Membrane
Outer Membrane
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
Synonym: gntU
Synonym: gluconate permease
Synonym: gnuT
Synonym: gntT
Replicon chromosome
Genomic location 2560762 - 2562114 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs


RefSeq NP_251012.1
GI 15597518
Affymetrix PA2322_at
Entrez 883019
GenBank AAG05710.1
INSDC AAG05710.1
NCBI Locus Tag PA2322
protein_id(GenBank) gb|AAG05710.1|AE004658_4|gnl|PseudoCAP|PA2322
UniParc UPI000012B8DA
UniProtKB Acc Q9ZIJ1
UniRef100 UniRef100_Q9ZIJ1
UniRef50 UniRef50_Q9ZIJ1
UniRef90 UniRef90_Q9ZIJ1


Feature Type CDS
Coding Frame 1
Product Name
Product Name Confidence: Class 2
Synonyms gluconate permease
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 2.40
Kyte-Doolittle Hydrophobicity Value 1.056
Molecular Weight (kDa) 47.3
Isoelectric Point (pI) 8.04

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 232 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001013 (836 members)
Putative Inparalogs None Found


STRING database Search for predicted protein-protein interactions using:
Search term: PA2322
Search term: gntP
Search term: GntP


Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res. 2005 Feb;15(2):321-9
PubMed ID: 15687295
The gntP gene of Escherichia coli involved in gluconate uptake.
Klemm P, Tong S, Nielsen H, Conway T
J. Bacteriol. 1996 Jan;178(1):61-7
PubMed ID: 8550444
Molecular genetic characterization of the Escherichia coli gntT gene of GntI, the main system for gluconate metabolism.
Porco A, Peekhaus N, Bausch C, Tong S, Isturiz T, Conway T
J. Bacteriol. 1997 Mar;179(5):1584-90
PubMed ID: 9045817
Gene organization and transcriptional regulation of the gntRKU operon involved in gluconate uptake and catabolism of Escherichia coli.
Izu H, Adachi O, Yamada M
J. Mol. Biol. 1997 Apr;267(4):778-93
PubMed ID: 9135111
Identification of GntR as regulator of the glucose metabolism in Pseudomonas aeruginosa.
Daddaoua A, Corral-Lugo A, Ramos JL, Krell T.
Environ Microbiol. 2017 Sep;19(9):3721-3733.
PubMed ID: 28752954