Pseudomonas aeruginosa PAO1, PA2387 (fpvI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2387
Name
fpvI
Replicon chromosome
Genomic location 2640392 - 2640871 (- strand)
Transposon Mutants 1 transposon mutants in PAO1

Cross-References

RefSeq NP_251077.1
GI 15597583
Affymetrix PA2387_at
DNASU PaCD00007042
Entrez 882249
GenBank AAG05775.1
INSDC AAG05775.1
NCBI Locus Tag PA2387
protein_id(GenBank) gb|AAG05775.1|AE004665_2|gnl|PseudoCAP|PA2387
TIGR NTL03PA02387
UniParc UPI00000C56A6
UniProtKB Acc Q9I193
UniProtKB ID Q9I193_PSEAE
UniRef100 UniRef100_W0YU72
UniRef50 UniRef50_Q4K9A6
UniRef90 UniRef90_Q5DIS4

Product

Feature Type CDS
Coding Frame 1
Product Name
FpvI
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 2.10
Kyte-Doolittle Hydrophobicity Value -0.530
Molecular Weight (kDa) 18.3
Isoelectric Point (pI) 7.77

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 315 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003140 (459 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2387
Search term: fpvI
Search term: FpvI

Human Homologs

References

Siderophore-mediated cell signalling in Pseudomonas aeruginosa: divergent pathways regulate virulence factor production and siderophore receptor synthesis.
Beare PA, For RJ, Martin LW, Lamont IL
Mol Microbiol 2003 Jan;47(1):195-207
PubMed ID: 12492864
Pyoverdine-mediated regulation of FpvA synthesis in Pseudomonas aeruginosa: involvement of a probable extracytoplasmic-function sigma factor, FpvI.
Rédly GA, Poole K
J Bacteriol 2003 Feb;185(4):1261-5
PubMed ID: 12562796
FpvIR control of fpvA ferric pyoverdine receptor gene expression in Pseudomonas aeruginosa: demonstration of an interaction between FpvI and FpvR and identification of mutations in each compromising this interaction.
Rédly GA, Poole K
J Bacteriol 2005 Aug;187(16):5648-57
PubMed ID: 16077110