Pseudomonas aeruginosa PAO1, PA3137

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3137
Name
Replicon chromosome
Genomic location 3519045 - 3520544 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_251827.1
GI 15598333
Affymetrix PA3137_at
Entrez 882603
GenBank AAG06525.1
INSDC AAG06525.1
NCBI Locus Tag PA3137
protein_id(GenBank) gb|AAG06525.1|AE004737_11|gnl|PseudoCAP|PA3137
TIGR NTL03PA03137
UniParc UPI00000C5925
UniProtKB Acc Q9HZ88
UniProtKB ID Q9HZ88_PSEAE
UniRef100 UniRef100_A0A0C7CRU1
UniRef50 UniRef50_A0A0A5I847
UniRef90 UniRef90_A6V2T6

Product

Feature Type CDS
Coding Frame 1
Product Name
probable major facilitator superfamily (MFS) transporter
Product Name Confidence: Class 3
Synonyms probable MFS transporter
Evidence for Translation
Charge (pH 7) 0.58
Kyte-Doolittle Hydrophobicity Value 0.698
Molecular Weight (kDa) 53.7
Isoelectric Point (pI) 7.19

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 472 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002463 (912 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3137

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Emr, an Escherichia coli locus for multidrug resistance.
Lomovskaya O, Lewis K
Proc Natl Acad Sci U S A 1992 Oct 1;89(19):8938-42
PubMed ID: 1409590