Pseudomonas aeruginosa PAO1, PA3148 (wbpI)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA3148
Name
wbpI
Replicon chromosome
Genomic location 3531751 - 3532815 (- strand)

Cross-References

RefSeq NP_251838.1
GI 15598344
Affymetrix PA3148_wbpI_at
DNASU PaCD00007384
Entrez 882693
GenBank AAG06536.1
INSDC AAG06536.1
NCBI Locus Tag PA3148
protein_id(GenBank) gb|AAG06536.1|AE004738_10|gnl|PseudoCAP|PA3148
TIGR NTL03PA03148
UniParc UPI00000DA113
UniProtKB Acc G3XD61
UniProtKB ID WBPI_PSEAE
UniRef100 UniRef100_G3XD61
UniRef50 UniRef50_G3XD61
UniRef90 UniRef90_G3XD61

Product

Feature Type CDS
Coding Frame 1
Product Name
UDP-N-acetylglucosamine 2-epimerase WbpI
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -5.92
Kyte-Doolittle Hydrophobicity Value 0.056
Molecular Weight (kDa) 38.9
Isoelectric Point (pI) 5.84

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database VFDB : VF0085
Category LPS O-antigen (P. aeruginosa)
Evidence
Host Organism
Notes
Reference

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 423 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002455 (233 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3148
Search term: wbpI

References

Molecular characterization of the Pseudomonas aeruginosa serotype O5 (PAO1) B-band lipopolysaccharide gene cluster.
Burrows LL, Charter DF, Lam JS
Mol. Microbiol. 1996 Nov;22(3):481-95
PubMed ID: 8939432
Pseudomonas aeruginosa B-band lipopolysaccharide genes wbpA and wbpI and their Escherichia coli homologues wecC and wecB are not functionally interchangeable.
Burrows LL, Pigeon KE, Lam JS
FEMS Microbiol. Lett. 2000 Aug;189(2):135-41
PubMed ID: 10930727