Pseudomonas aeruginosa PAO1, PA3181

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA3181
Name
Synonym: edaA
Replicon chromosome
Genomic location 3570941 - 3571603 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251871.1
GI 15598377
Affymetrix PA3181_at
DNASU PaCD00007402
Entrez 882580
GenBank AAG06569.1
INSDC AAG06569.1
NCBI Locus Tag PA3181
protein_id(GenBank) gb|AAG06569.1|AE004742_5|gnl|PseudoCAP|PA3181
TIGR NTL03PA03181
UniParc UPI00000D4288
UniProtKB Acc O68283
UniProtKB ID ALKD_PSEAE
UniRef100 UniRef100_O68283
UniRef50 UniRef50_O68283
UniRef90 UniRef90_O68283

Product

Feature Type CDS
Coding Frame 1
Product Name
2-keto-3-deoxy-6-phosphogluconate aldolase
Product Name Confidence: Class 2
Synonyms KDPG-aldolase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 1.32
Kyte-Doolittle Hydrophobicity Value 0.022
Molecular Weight (kDa) 24.0
Isoelectric Point (pI) 7.55

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 2
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 372 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002435 (548 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3181

References

The folding and quaternary structure of trimeric 2-keto-3-deoxy-6-phosphogluconic aldolase at 3.5-A resolution.
Mavridis IM, Tulinsky A
Biochemistry 1976 Oct;15(20):4410-7
PubMed ID: 974067
Complete primary structure of 2-keto-3-deoxy-6-phosphogluconate aldolase.
Suzuki N, Wood WA
J. Biol. Chem. 1980 Apr;255(8):3427-35
PubMed ID: 6988426