Pseudomonas aeruginosa PAO1, PA3191 (gtrS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA3191
Name
gtrS
Replicon chromosome
Genomic location 3582171 - 3583592 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_251881.1
GI 15598387
Affymetrix PA3191_at
Entrez 882906
GenBank AAG06579.1
NCBI Locus Tag PA3191
protein_id(GenBank) gb|AAG06579.1|AE004743_2|gnl|PseudoCAP|PA3191
TIGR NTL03PA03191
UniProtKB Acc Q9HZ47
UniProtKB ID Q9HZ47_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
glucose transport sensor, GtrS
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -2.39
Kyte-Doolittle Hydrophobicity Value -0.111
Molecular Weight (kDa) 53.0
Isoelectric Point (pI) 6.60

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Virulence Evidence

Source 1
Database PseudoCAP
Category
Evidence ECO:0000314
direct assay evidence used in manual assertion
Host Organism Mus musculus
Notes
Infection model Mouse model of acute pneumonia
Reference 22262100

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 621 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002425 (544 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3191
Search term: gtrS

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res. 2005 Feb;15(2):321-9
PubMed ID: 15687295
A novel host-responsive sensor mediates virulence and type III secretion during Pseudomonas aeruginosa-host cell interactions.
O'Callaghan J, Reen FJ, Adams C, Casey PG, Gahan CG, O'Gara F
Microbiology (Reading, Engl.) 2012 Apr;158(Pt 4):1057-70
PubMed ID: 22262100