Pseudomonas aeruginosa PAO1, PA3193 (glk)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3193
Name
glk
Replicon chromosome
Genomic location 3584379 - 3585374 (- strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_251883.1
GI 15598389
Affymetrix PA3193_glk_at
DNASU PaCD00007407
Entrez 882908
GenBank AAG06581.1
INSDC AAG06581.1
NCBI Locus Tag PA3193
protein_id(GenBank) gb|AAG06581.1|AE004743_4|gnl|PseudoCAP|PA3193
TIGR NTL03PA03193
UniParc UPI000012B62D
UniProtKB Acc Q9HZ46
UniProtKB ID GLK_PSEAE
UniRef100 UniRef100_B7V9H3
UniRef50 UniRef50_B7V9H3
UniRef90 UniRef90_B7V9H3

Product

Feature Type CDS
Coding Frame 1
Product Name
glucokinase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -7.71
Kyte-Doolittle Hydrophobicity Value 0.247
Molecular Weight (kDa) 34.6
Isoelectric Point (pI) 5.00

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 219 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002423 (527 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3193
Search term: glk
Search term: glucokinase

Human Homologs

References

Molecular characterization of glucokinase from Escherichia coli K-12.
Meyer D, Schneider-Fresenius C, Horlacher R, Peist R, Boos W
J Bacteriol 1997 Feb;179(4):1298-306
PubMed ID: 9023215